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SMALP Copolymers
play a pivotal role in the study of membrane proteins by providing tools for their solubilization, stabilization, purification, and functional reconstitution
- solubilization and stabilization agent for isolating active membrane protein in their native environment
- detergent-free solution, no need for detergents, not even downstream
- allows to solubilize membrane proteins while maintaining their native structure and functionality
- can solubilize membrane proteins directly from biological membranes to form nanodiscs (SMALP – styrene maleic acid lipid particles)
- SMALPs provide a more native-like environment for the proteins, allowing for more accurate functional studies
- sustainable development: supports the United Nation's goal of good health and well-being